EGFR and non-small cell lung carcinoma: A comparison of an adnectin-based CAR and an scFv-based CAR showed that adnectin-based EGFR-targeted CARs have similar efficacy in targeting EGFR+ cells when compared to an scFv-based EGFR CAR in both in vitro and in non-small cell lung cancer xenograft murine models [91].