NGF and Alzheimer disease: The recent realization that the degeneration of BFCNs in AD predicts the atrophy of brain regions innervated by their projections, such as the entorhinal cortex and cerebral cortex [87,88,89,90], is a further invitation to considering the best strategies to protect the NGF-dependent BFCNs from their unavoidable atrophy as the AD pathology progresses.