GCLC and fetal growth restriction: Studies that assessed the antioxidative impacts of dietary curcumin in IUGR pigs found that curcumin improved jejunal oxidative stress through activation of Nrf2, glutamate-cysteine ligase catalytic subunit (GCLC), superoxide dismutase 1 (SOD1), glutamate-cysteine ligase modifier subunit (GCLM) and NAD(P)H quinone dehydrogenase 1 (NQO1).