Finally, in the fully adjusted model, higher NAE remained directly associated with greater GFR (3.07; 95% CI: 1.87 to 4.27; p < 0.001), higher insulin resistance (1.76; 95% CI: 0.55 to 2.98; p = 0.005), and higher PRAL (1.79; 95% CI: 0.56 to 3.03; p = 0.004). The gene discussed is PRAL; the disease is Insulin resistance.