Furthermore, the dermal inflammation of sham group (p < 0.001), KRG + AH group (p < 0.001), CS group (p = 0.004), KRG + CS group (p < 0.001), and KRG + EPO group (p < 0.001) was found to be significantly lesser than AD group (Figure 2C). This evidence concerns the gene EPO and Alzheimer disease.