INS and Hypoinsulinemia: At the end of the 17-week experiment, the HFD mice exhibited increased levels of fasting blood glucose, serum insulin, serum cholesterol, serum triglycerides, serum AST and serum ALT, all of which were alleviated by MLB supplementation (Figure 2A,B,D–G), indicating that MLB can induce hypoglycemia, hypoinsulinemia, and hypolipidemia, and improve liver function.