TNF and breast cancer: It has been reported that adipokines produced by adipocytes, which secrete ILs, TNF-α, and hepatic growth factor, support the growth of BC by transferring fatty acids to enhance mitochondrial oxidation, extracellular matrix remodeling, and endotrophin production from collagen, supporting the growth of BC by transferring fatty acids to enhance mitochondrial oxidation, extracellular matrix remodeling, and endotrophin production from collagen [138].