Thus far, it is not possible to explain the decrease in gut hormones observed in this study, but a very significant correlation was found between the change in ghrelin and the change in HbA1c during the intervention (Pearson’s coefficient = 0.412; p = 0.001) implying that ghrelin decrease was related to glucose control improvement, which is consistent with reported hyperglycemic and insulin resistance promoting effects of acyl ghrelin [35]. The gene discussed is GHRL; the disease is Insulin resistance.