CCN2 and metabolic dysfunction-associated steatohepatitis: Previous studies, including ours, strongly indicated that expression of inflammatory cytokines associated with inflammation (Tnf-α, Il-6, Il-18, Ifn-γ, and Il-1β) and fibrosis (Tgf-β1, Timp1, Timp2, Col1a1, and Ctgf) correlated with histological NASH activity in human and rodent models [15,26,27,28].