A simple linear regression analysis revealed that DM (r = 0.186, p = 0.042), SBP (r = 0.338, p = 0.001), and age (r = 0.355, p < 0.001), and log-CRP (r = 0.249, p = 0.006), log-BUN (r = 0.246, p = 0.007), log-creatinine (r = 0.348, p < 0.001), log-iPTH (r = 0.297, p = 0.001), and OPN (r = 0.536, p < 0.001) were positively correlated with cfPWV. The gene discussed is SPP1; the disease is diabetes mellitus.