When evaluating the pattern of adiponectin in the presence of obesity and biochemical alterations, it was observed that greater weight, waist circumference, and concentrations of triglycerides, very low density lipoproteins, and insulin were associated with a decrease in the adiponectin concentration (p < 0.05) (Table 5). This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.