In our research, aiming to study SP/NK1R in OSCC [72], we described a significantly higher immunostaining of SP in both cell membrane and cytoplasm than in cancer cells’ nuclei, supporting the association found with a higher cell proliferation index by measuring ki67 expression in tumour tissues, as NK1R, once internalized, promotes cell proliferation (Figure 1). The gene discussed is TACR1; the disease is neoplasm.