The acetylcholinesterase inhibitory effect and mechanism of action of α-pinene is therefore beneficial for the prevention and progression of neurodegenerative disease such as Alzheimer’s disease, which is associated with a decline in levels of acetylcholine due to cholinergic neuron deterioration, which results in memory loss-an important characteristic of the neurodegenerative disease [1]. This evidence concerns the gene ACHE and neurodegenerative disease.