Nevertheless, authors have compared their in vitro anticancerous properties on chemosensitive models of breast cancer (MDA-MB-231-pcDNA3), colon cancer (HCT116 p53+/+), leukemia (CCRF -CEM) and glioblastoma (U87 MG), as well as on corresponding chemoresistant models of breast cancer MDA-MB-231-BCRP-clone 23, colon cancer HCT116 p53−/−, CEM/ADR-5000 leukemia and U87MG.ΔEGFR glioblastoma. The gene discussed is TP53; the disease is leukemia.