Through the promotion of glutamine metabolism, the c-MYC oncogene could partially modulate cancer metabolic reprogramming, favoring cancer cell growth and survival by the upregulation of the c-MYC-target and mTORC1 pathway in KD-SDHB hPheo1 cells, as is demonstrated from the microarray data, where GLUD1 expression is enhanced to induce glutaminolysis. This evidence concerns the gene MYC and cancer.