MAP1LC3A and supranuclear palsy, progressive, 1: In the PSP cases, the SNc neurons immunolabeled for FtMt and LC3 showed varied staining characteristics that could be roughly categorized into three patterns: The first pattern showed numerous puncta with strong FtMt-IR, fewer puncta with weak-to-moderate LC3-IR, and a limited degree of colocalization between both (pattern 1, Figure 3D–F).