The percentage of LAP1-positive deformed nuclei in DM1 patient-derived fibroblasts tended to be higher than in the control fibroblasts, and this increase was more pronounced in fibroblasts with a higher CTG repeat length (DM1_2000 vs. control: p = 0.0301) (Figure 5E). Here, TOR1AIP1 is linked to myotonic dystrophy type 1.