Additionally, the DM1 patient-derived fibroblasts that were immunolabeled for emerin presented a higher percentage of deformed nuclei than the control fibroblasts (DM1_1000 vs. control: p = 0.0245; DM1_2000 vs. control: p = 0.0032) (Figure 4E). This evidence concerns the gene EMD and myotonic dystrophy type 1.