FTC is a less common subtype of WDTC with 10–15% cases of all the thyroid carcinomas, driven by RAS, BRAFV600E mutations, and PAX8/PPARγ (Paired Box Gene 8/Peroxisome Proliferator-Activated Receptor Gamma) rearrangements. The gene discussed is PAX8; the disease is thyroid cancer, nonmedullary, 2.