In the previously published studies, Q-3-G has been used to inhibit ear edema, peritoneal permeability, and pulmonary edema [50], acting as a potent antioxidant in blood plasma with low-density lipoprotein [42], decreasing peroxynitrite-induced oxidative modification [51], exerting an anti-inflammatory effect by inhibiting JNK and ERK signaling pathways under LPS challenge [52], and possessing anticancer properties against breast cancer cells [56]. Here, MAPK8 is linked to pulmonary edema.