This cytokine is involved in the maintenance of inflammatory reaction through (1) the recruitment and accumulation of eosinophils via the upregulation in nasal polyps of the chemokine eotaxin and the adhesion molecule VCAM-1 [10,39,40] (2) the accumulation of CCL2, a monocyte chemoattractant, in fibroblast cultures derived from nasal polyps [41]. Here, VCAM1 is linked to Nasal polyposis.