Cytokines and chemokines regulate innate and adaptive immune responses, and elevated levels of various pro-inflammatory interleukins (IL1β, IL-2, IL-4, IL-6, IL-8), interferon (IFN)-γ, monocyte chemotactic protein 1, and anti-inflammatory interleukins such as IL-10 in the vitreous humor of patients with RP suggest that these molecules mediate or regulate the immune response in RP. The gene discussed is IL10; the disease is retinitis pigmentosa 1.