In gastric cancer cells, miR-423-5p regulates cell proliferation and invasion by targeting trefoil factor 1 [15], and in hepatocellular carcinoma, miR-423-3p overexpression promotes cell growth and regulates G1/S transition by targeting p21Cip/WaF1, a tumor suppressor gene [13]. The gene discussed is CDKN1A; the disease is hepatocellular carcinoma.