BRCA1 and cancer: As a consequence of interacting with these different proteins, BRCA1 plays pleotropic roles, including DNA damage resistance, ubiquitination, gene transcription, and cell cycle progression, such as G2-M checkpoint control [24] (detailed information is found in Molecular Diagnosis and Targeting for Gynecologic Malignancy, ISBN 978-981-33-6013-6 (eBook)) [25].