Furthermore, Ikemori et al. detected galectin-3 expression in pseudopalisades [98], which are regions that comprise cells that actively migrate away from hypoxic or necrotic foci [126], and found that hypoxia induced galectin-3 expression, which protects glioma cells from oxygen- and nutrient-deprivation-induced cell death. The gene discussed is LGALS3; the disease is glioma.