TNF and myeloid sarcoma: A Th1 cytokine profile was predominant in cell cultures of REM-MS patients stimulated with VZV, in agreement with studies of systemic memory T-cells expressing IFN-γ, TNF and IL-2 in latent VZV infected individuals [34] and coinciding with reports that MS should be considered a Th1/Th17 driven disease [35,36].