DNTTIP1 and non-small cell lung carcinoma: When NSCLC cells were treated with the LSD1 inhibitor sp2509, both H3K4me2 and RpolII were enriched at the E-cadherin promoter, as expected, suggesting that TdIF1 acts by recruiting LSD1, which in accordance with our observation that RpolII was enriched after treatment with siTdIF1 (Figure 4D).