Among the investigations of PD-L1 regulation in NSCLC with KRAS mutation, Chen et al. found that upregulation of PD-L1 mRNA expression induced by KRAS activation resulted from phosphorylation of extracellular signal-regulated kinase (ERK), but not phosphorylation of AKT [52]. Here, AKT1 is linked to non-small cell lung carcinoma.