After checking the gene co-expression networks in NSCLC patient tumors in GSE31800 and GSE28582, XRCC5 from KD_NON_HOMOLOGOUS_END_JOINING pathway was found to have the same gene co-expression patterns in patient tumors as in shRNA knock-down in A549 cell line (Figure 6B; Table 6). The gene discussed is XRCC5; the disease is non-small cell lung carcinoma.