TIMP1 and neoplasm: In addition, TARBP2 is reported to promote tumor-induced angiogenesis through degradation of mRNAs coding for antiangiogenetic factors, including thrombospondin1/2 (THBS1/2), tissue inhibitor of metalloproteinases 1 (TIMP1), and serpin family F member 1 (SERPINF1) [8].