PLOD1 and type 2 diabetes mellitus: Indeed, in this study we have shown that the stimulating effects of single-dose hCG on testosterone production in T2DM rats were less pronounced than in the control animals (Table 2, Figure 1), and this is in agreement with our early data on the weakening of the gonadotropin steroidogenic effect in T2DM and T1DM rats with reduced LH/hCG-R content in the testes [38,43].