CDH1 and neoplasm: Remarkably, an area with a newly formed tumor bud-like structure invading into the stroma was characterized by strong GFP expression, a decrease in cell–cell junctional E-cadherin staining (arrows in Figure 3F,G,G′), and an enrichment in a newly formed vasculature in the vicinity of the GFP-positive cells (asterisks in Figure 3F,G,G′).