Our study using mice with Lewis lung carcinoma cells injected subcutaneously (to monitor the tumor growth on a daily basis) showed that montelukast significantly hampered the tumor growth, and the tumor tissue of the montelukast group showed markedly decreased Ki-67 expression and markedly increased terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL)-positive cells [77]. Here, MKI67 is linked to neoplasm.