Using mouse embryonic fibroblasts as a cancer metabolic reprogramming mimic model, their study indicated that C/EBPβ-LIP changed the mitochondrial respiration and served as a transcription factor to regulate the Let-7 family—including Let-7a, Let-7b, Let-7c, Let-7d, Let-7f, Let-7g, and Let-7i—consequently modulating cell glycolysis, proliferation, tissue regeneration, and carcinogenesis [111]. This evidence concerns the gene CEBPB and cancer.