The in vivo mice model of influenza-induced respiratory disease highlighted the potential beneficial effects of MIM against viral-mediated respiratory diseases as a preventive and early treatment, as MIM acted at (i) a local level, in promoting the recruitment of neutrophils to the lungs, and (ii) at a systemic level, in increasing the circulating levels of IgM in the treated animals, compared with the control group. The gene discussed is CD40LG; the disease is influenza.