In patients with advanced BCs in advanced stage (TNM III and IV), downregulated miR-203a-3p, and SNAI2 with ZEB1 were detected in TU-C and TU-IF, and upregulation of SNAI1 and miR-205-5p was found in samples with disseminated cancer cells, LNM and CD45-DB fractions, respectively. The gene discussed is SNAI2; the disease is cancer.