As expected, the methylation status of SKP1 varies by cancer type, with SKP1 being hypomethylated (i.e., expressed) in the majority of colorectal, head and neck, ovarian, stomach and uterine cases, whereas it tends to be partially or hypermethylated (i.e., repressed) in bladder, breast, lung and pancreatic cancers. This evidence concerns the gene SKP1 and cancer.