However, confirming our results, another group reported non-neoplastic stratified epithelial tissue adjacent to squamous cell carcinoma (SCC) from the cervix, esophagus and head and neck, presenting with strong membranous Trop-2 staining of differentiated keratinocytes in the stratum spinosum, stratum granulosum and stratum corneum. This evidence concerns the gene TACSTD2 and squamous cell carcinoma.