Medium Trop-2 expression was furthermore described for the squamous epithelial cells of the oral mucosa [12,13] Moreover, the (over-)expression of Trop-2 had been found in a variety of human malignancies, e.g., cancer of the lung, prostate, pancreatic, gastric, colorectal, breast, cervix, ovarian, esophageal and urinary bladder cancer (summarized in [11,14]). This evidence concerns the gene TACSTD2 and lung carcinoma.