LGALS13 and fetal growth restriction: While Chaftez et al. showed that low levels of first-trimester PP13 were associated with preterm birth in women with IUGR [109], Cowans and colleagues found that decreased serum levels of galectin-13 were not significantly correlated with the studied adverse pregnancy outcomes of IUGR, preterm low birth weight and intrauterine fetal demise [110].