Results from our laboratory suggest a role for galectin-3 in the inflammatory response in chorioamniotic infection and preterm premature rupture of membranes (PPROM), considering its overexpression in chorioamniotic membranes in women with PPROM and histologically confirmed intraamniotic infection compared to those with PPROM without chorioamnionitis [79]. Here, LGALS3 is linked to chorioamnionitis.