✓a selective inhibitor of L-lactate dehydrogenase A chain (LDHA) (IC50 = 3 nM) and LDHB (IC50 = 5 nM) [258]✓reduces p-RPS6 (235/236) and p-p70S6K (T389) only in glycolysis-dependent cancer cell lines [114]. This evidence concerns the gene LDHB and cancer.