✓a fatty acid synthase (FASN) inhibitor (IC50 = 35 μM) [233]✓induces apoptosis and downregulates both p-RPS6 (S240/244) and t-RPS6 via AKT/mTOR/SK6 axis by stimulating protein ubiquitination in ovarian cancer cells [173]. The gene discussed is RPS6; the disease is ovarian cancer.