CD274 and non-small cell lung carcinoma: ✓a specific inhibitor of p70S6K1 (IC50 = 3 nM) and p70S6K2 (IC50 = 35 nM) and reduces p-RPS6 (S235/236) and p-RICTOR (T135) [254]✓reduces p-RPS6 (S235/236) and induces PD-L1 in H460 and HCC827 NSCLC cell lines [150]