✓an enzyme catalyzes A-to-I RNA editing (deamination of adenosine to inosine in double-stranded RNA) [161]✓ADAR1-KD induces cell death and growth arrest in vitro, downregulates p-RPS6 (S235/236), p-mTOR (S2448), and p-p70S6K (T389) in gastric cancer (GC) cells, and attenuates tumorigenicity and metastasis of GC cells in vivo [162]✓Overexpression of ADAR1 increases p-RPS6 (S235/236), p-mTOR (S2448), and p-p70S6K (T389) in GC cells. The gene discussed is RPS6; the disease is gastric cancer.