✓a selective inhibitor for PI3K p110α (IC50 = 0.3 μM) [320]✓reduces p-RPS6 (S235/236 and S240/244) and p-AKT (S473) in the SCLC cell line H69, and concomitantly reduces the cell viability by inducing apoptosis and autophagy [131]. The gene discussed is RPS6; the disease is small cell lung carcinoma.