PGF and placenta disorder: Quintero-Renderos et al. demonstrated Forkhead Box D1 (FOXD1) mutations’ central role in recurrent pregnancy loss (RPL), recurrent implantation failure (RIF), FGR and PE pathogenesis via complement C3 and placental growth factor (PlGF) regulation and described a functional link between FOXD1 and implantation and placental diseases [72].