Furthermore, mRNA expression of microtubule-associated protein tau (MAPT), associated with increased risk for AD and PD [44,45], was reduced by 65% in NDD-D patients (p < 0.001) (Figure 3C) but was five-fold higher in NDD-PD individuals (Figure 3D) than in subjects with no NDDs. This evidence concerns the gene MAPT and Alzheimer disease.