These findings show that the downregulation of soluble NOX2-derived peptide (sNOX2-dp) and the decreased excretion of F2-isoprostanes (F2-IsoP) have a strong relationship with adherence to the Med-Diet and could lead to a reduction of cardiovascular events in AF patients, through an antioxidant effect [83]. Here, CYBB is linked to atrial fibrillation.