TGF-β, among other inflammatory cytokines, is a key regulator of fibroblast to myofibroblast differentiation during wound healing and cancer-associated fibroblasts (CAFs) transition in various cancers [43], including prostate, breast, pancreatic, bladder and colorectal cancer [44,45,46,47,48,49,50]. The gene discussed is TGFB1; the disease is cancer.