The TNBC SUM1315M02 (BRCAmut), HER2+/hormone receptor positive (HR+) breast cancer cell lines SKBR3 and MCF7 (BRCAwt) did not show significant changes upon treatment with [125I]-PARPi-01 all one and in combination with Dox-NP. This evidence concerns the gene ERBB2 and breast cancer.