CSF3 and neoplasm: Hematopoietic stem and progenitor cells (HSPCs) and myeloid progenitors (MyP) can sense and are responsive to a variety of mediators that are released by tumor cells, such as granulocyte-colony stimulating factor (G-CSF), granulocyte macrophage (GM)-CSF or the chemokine CXCL-12 [33,34].