Only 2% of gastric MALT patients showed the concomitance of TP53 mutation and allele loss, but 22% of DLBCL displayed both TP53 mutation and allele loss, suggesting that TP53 partial inactivation might play a role in the development of low-grade MALT lymphomas, whereas complete inactivation might be associated with high-grade transformation [149]. The gene discussed is TP53; the disease is MALT lymphoma.