TET2 and MALT lymphoma: In MALT lymphomas, TET2 inactivation may deregulate the expression of transcriptional factors indispensable for B-cell function, and thus potentially cooperate with receptor signalling, including those by the enhanced T-helper cell signals, indirectly triggered by PD-L1/TNFRSF14 inactivation in malignant B-cells [128].