Immunohistochemical (IHC) analysis of a tissue microarray panel of T-cell lymphomas composed of primary tissue biopsies were also positive for BRG1 expression in all ALK+ ALCL patients analysed, with the majority showing strong expression (present in >30% of tumour cells; 12/12 cases positive: 2 cases +, 10 cases ++ staining) (Figure 1b–d). This evidence concerns the gene SMARCA4 and anaplastic large cell lymphoma.