ALK and anaplastic large cell lymphoma: Previous studies have shown that BRG1 immunoprecipitates with an amino-terminal NPM1 antibody in the NPM-ALK+ ALCL cell line KARPAS-299, suggesting that it is part of a complex with NPM-ALK (NPM1 also binds to NPM-ALK via the oligomerisation domain of NPM retained in the fusion protein which allows its nuclear translocation) [14].