TMEM45A protein expression has been published in several cancer cell lines, such as MDA-MB-231 breast cancer cells and in HepG2 human hepatoma cells [44], and in several other cancers such as human cervical lesions [69], ovarian cancer [70], glioma [71,72], renal cell carcinoma [73,74,75], colorectal cancer [76], head and neck cancer [75], and invasive breast cancer [77]. This evidence concerns the gene TMEM45A and hereditary clear cell renal cell carcinoma.