Namely, GLUT1 (solute carrier family 2, facilitated glucose-transporter member 1), MCT4 (monocarboxylate transporter 4), CA9 (carbonic anhydrase 9), TMEM45A, CD66 (carcinoembryonic antigen-related cell adhesion molecules), CD24 (signal transducer CD24), and EGFR (epidermal growth factor receptor) targets were selected by differential expression in xenografts versus a two-dimensional cell culture of A549 cells analyzed using a 624 gene-based human cancer panel [27]. Here, CA9 is linked to cancer.