From these cultures, antitumor IFN-γ–producing T cells were generated 5 days after SC inoculation with A20 tumor in Balb/c mice, and these IFN-γ–producing T cells primarily comprised the CD44high memory T-cell, leading to immune protection from tumor re-challenge over 100 days after regression of the primary tumors. The gene discussed is IFNG; the disease is neoplasm.