BMDCs contribute as various cells in TME such as αSMA-positive cancer-associated fibroblasts (CAFs) [13], CD34-positive tumor-associated endothelial cells (TECs) [14], and CD11b-positive tumor-associated macrophages (TAMs) [15] and facilitate tumorigenesis, invasion, and metastasis. The gene discussed is ITGAM; the disease is neoplasm.